Infant discomfort

Editorially verified for the Oct 16, 2026

40 Across

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A caregiver gently soothing an infant

Clue explainedFact checked

Colic is the term for episodes of prolonged crying and apparent discomfort in an otherwise healthy infant. It’s often associated with stomach trouble, though the precise cause can be unclear; the word here names the familiar kind of infant distress.

Clue type:
Definition

NYT Crossword

This clue's Friday, October 16, 2026 appearance

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Across

  1. 1Word with strip or skirt
  2. 6Conniption
  3. 9Cuban poet/philosopher José
  4. 142000 hit song with the lyric "But to lose all my senses / That is just so typically me"
  5. 17Mail-centric fiction?
  6. 18Virginia is in it, in brief
  7. 19"Hah!"
  8. 20"___ had it!"
  9. 21Former home of Mr. and Mrs. Met
  10. 23"The Mary Tyler Moore Show" spinoff
  11. 24Riot
  12. 25Spiller of tea
  13. 27Smelling things?
  14. 28Date night viewing, often
  15. 34High concept?
  16. 35They explain what's in the cards
  17. 39Comic strip sound of impact
  18. 40Infant discomfort
  19. 42Battery-powered string instrument player
  20. 43Predicated
  21. 48It has its highs and lows
  22. 49Rocky openings?
  23. 50Burrowing animal whose name is made up of two other animals
  24. 52It may begin with a +1: Abbr.
  25. 53Idolizes
  26. 56Indiana Jones or Rocky Balboa, e.g.
  27. 57Losing causes?
  28. 58Yoga ___
  29. 59The 22nd Amendment limits them

Down

  1. 1"Piece of cake!"
  2. 2Reality show whose contestants report to the Judge's Table
  3. 3Not gendered
  4. 4Dope
  5. 5Some emergency resources
  6. 6Serious dirt
  7. 7State whose official fruit is the huckleberry
  8. 8Done to death
  9. 9Flow down the neck
  10. 10Past word
  11. 11Hot pockets?
  12. 1220-20, e.g.
  13. 13Small sounds
  14. 15One of 412 in the White House
  15. 16Supermodel Banks
  16. 22Took back one's words
  17. 24One struggling to make ends meet
  18. 26Grant
  19. 27Foe of Dr. Eggman, in video games
  20. 29Procured
  21. 30"___ Share of Night" (acclaimed 2019 Mariana Enríquez book)
  22. 31Complimentary lines
  23. 32Tool for tracing family trees
  24. 33Prefix with the name of any month
  25. 35Mideast salad, in one spelling
  26. 36Simon the Zealot, e.g.
  27. 37Sparkly bits in a school art project
  28. 38Like some deliveries
  29. 39Holder of all the digits, from 1 to 0
  30. 41Stage-left orchestra section
  31. 43Coccyx or phalange, e.g.
  32. 44Unwelcome sound during a dream
  33. 45Brown tint
  34. 46Construct
  35. 47Art movement proclaimed in a 1916 manifesto
  36. 50May honorees
  37. 51Outdoor item with flaps
  38. 54Took a load off
  39. 552011 platinum single by Tyler, the Creator

The answer to “Infant discomfort” in the New York Times crossword is COLIC — a 5-letter word. It most recently appeared in the New York Times crossword on October 16, 2026, a Friday puzzle, at 40-Across. Below you'll find why that fill fits, every other answer we've recorded for this clue, and links into the puzzle it came from.

“Infant discomfort” answer

COLIC (5 letters)

Reveal the solution one letter at a time with the tiles above if you'd rather nudge yourself toward it than see the whole word at once. Just want it outright? The answer is COLIC.

What does COLIC mean?

Reading the plain dictionary sense of COLIC is often the fastest way to see why it answers this clue.

(noun)

  • severe pain in the abdomen caused by wind or obstruction in the intestines and suffered especially by babies

When else has “Infant discomfort” appeared?

New York Times reuses clues across dates, sometimes with a different answer depending on the grid. Here's where this exact clue has shown up, and what the answer was each time — handy when you're checking whether today's fill is the only one.

October 16, 2026 (most recent) → COLIC. We haven't indexed another appearance of this exact clue yet.

Frequently asked questions

What is the answer to “Infant discomfort”?

The answer is COLIC, a 5-letter word. It most recently appeared in the New York Times crossword on October 16, 2026.

How many letters is the answer to “Infant discomfort”?

5 letters: COLIC.

When did this clue appear?

Most recently in the New York Times crossword on October 16, 2026 (a Friday puzzle), at 40-Across.

Can “Infant discomfort” have a different answer?

Yes — New York Times sometimes reuses a clue with a different solution to fit the grid. The answers we've recorded for each date it appeared are listed above when available.

Where can I find the rest of this day's NYT Crossword answers?

The full grid for October 16, 2026 is on the NYT Crossword answers page, with every clue and answer from that puzzle.

New York Times Crossword is published by The New York Times; WordHint is an independent site and is not affiliated with or endorsed by the publisher.

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